Cytomegalovirus retinitis in patients of non-Hodgkin’s lymphoma: clinical presentations and outcomes

Abstract Background Cytomegalovirus (CMV) retinitis in patients with Non-Hodgkin’s Lymphoma (NHL) can occur even the presence of high CD 4 counts and behave differently when compared to CMV human immunodeficiency (HIV) patients. It, therefore, becomes important understand its varied presentations challenges management these cases. The aim this study was analyse various patterns outcomes Retinitis NHL. Study design A retrospective chart review seven eyes four NHL presenting between June 2017 May 2020 done. Methods Clinical Retinitis, CD4 at time presentation duration treatment along recurrences for recurrence were assessed. Results Granular or indolent (6 out 7 eyes) commonest form Three had a count above 150 cells/mm 3 none them below 50 . Floaters complaint. All vitritis majority (3 4) anterior chamber (AC) inflammation. Two (mean 33.8 days) after stopping maintenance phase ganciclovir one patient significant myelosuppression related oral valganciclovir which required discontinuation drug. Conclusion is usually an granular type as HIV. These may require long term view frequent treatment.